Diecezja Białostocka
Diecezja Bydgoska
Diecezja Gdańska
Diecezja Kaliska
Diecezja Katowicka
Diecezja Krakowska
Diecezja Lubelska
Diecezja Łódzka
Diecezja Pelplińska
Diecezja Poznańska
Diecezja Rzeszowska
Diecezja Wrocławska
Diecezja Zielonogórsko-Gorzowska
Diecezje Warszawskie

Jak złagodzić COVID-19?

Wzmacniaj układ odpornościowy! 
Jego stan jest kluczowy w przebiegu infekcji koronawirusem SARS-CoV-2. 
 
PROFILAKTYKA w okresie wzmożonej zachorowalności
Witamina D3                        1000-3000 IU dziennie
Witamina C                          3-5 dziennie po 200 mg
Witamina B complex           1x dziennie 1 tabl.
Witamina B12 forte             100 μg dziennie
Cynk                                   30-40 mg dziennie
Olej z czarnuszki                40 mg/1 kg masy ciała dziennie
Kwercetyna*                       250 mg dziennie
Miód
 
Zadbaj także 
• o pożyteczną florę bakteryjną w jelitach 
• o właściwy stan błony śluzowej nosa i gardła
• o higienę psychiczną: relacje, życzliwość, poczucie sensu. Lęk, niepokój, zaburzenia snu, obniżony nastrój osłabiają odporność. Znajdź bratnią duszę!heart
 
Masz pozytywny wynik testu? Podejrzewasz, że masz koronawirusa? Pojawiły się objawy…
Nie zwlekaj! Poza właściwą terapią wspomagaj organizm w walce z chorobą! 
 
PODCZAS LECZENIA:
Witamina D3                         4000-5000 IU dziennie
Kwas acetylosalicylowy**     100-150mg - 1 tabl. dojelitowa dziennie
Cynk                                      75-100mg dziennie
Witamina C                           1000-2000mg dziennie w dawkach po 200 mg
Witamina B complex             3 x dziennie 1 tabl.
Witamina B12 forte               100 μg 2 x dziennie 
Melatonina                            3-5 mg przed snem
Probiotyki                              1 x dziennie
Olej z czarnuszki                  80 mg/1 kg masy ciała dziennie
Kwercetyna*                         250 mg dziennie
Kurkumina                            500 mg 2 x dziennie
Miód                                     1g/1kg masy ciała dziennie
Bądź w kontakcie z Bliskimi!heart
 

* Osoby mające problemy z tarczycą nie powinny przyjmować dużych dawek kwercetyny. Badania in vitro wykazały, że kwercetyna i inne flawonoidy zakłócają syntezę hormonów tarczycy. U kobiet wysokie spożycie soi było związane z podwyższonym stężeniem TSH tarczycy, może to zależeć od dawki, dlatego w przypadku przewlekłego stosowania profilaktycznego sugerujemy przyjmowanie najmniejszą dawkę. Kwercetynę należy stosować ostrożnie u pacjentów z niedoczynnością tarczycy. Poziom TSH powinien być monitorowany. Należy również zwrócić uwagę na fakt, że kwercetyna może wchodzić w istotne interakcje interakcje. Najważniejszą interakcją jest interakcja z cyklosporyną i takrolimusem.  U pacjentów przyjmujących te leki najlepiej jest unikać kwercetyny; jeśli kwercetyna jest przyjmowana, należy kontrolować stężenie cyklosporyny i takrolimusu.

** Nie podawaj dzieciom poniżej 12 roku życia. Nie łącz jednocześnie z innymi lekami przeciwzakrzepowymi. W przypadku przyjmowania ibuprofenu lub naproksenu zachowaj odstęp przynajmniej 6 godzin. 

Należy unikać długotrwałego stosowania dużych dawek cynku (> 50mg dziennie), ponieważ wiąże się to z niedoborem miedzi.

Tymochinon (aktywny składnik czarnuszki) zmniejsza wchłanianie cyklosporyny i fenytoiny. Pacjenci przyjmujący te leki powinni zatem unikać przyjmowania czarnuszki. Ponadto, zgłoszono dwa przypadki zespołu serotoninowego u pacjentów przyjmujących czarnuszkę, którzy poddani zostali znieczuleniu ogólnemu (prawdopodobna interakcja z fentanylem). 

 
Opracowano na podstawie:
FLCCC_Protocols_A_Guide_to_the.pdf
Fatima S, Zaidi SS, Alsharidah AS et al. Possible prophylactic approach for SARS-CoV-2 infection by combination of melatonin, Vitamin C and Zinc in animals. Fronteirs in Veterinary Science 2020; 7:585789.
Arslan B, Ergun NU, Topuz S et al. Synergistic effect of quercetin and vitamin C against COVID-19: Is a possible guard for front liners? ssrn 2020.
Ahmed AK, Albalawi YS, Shora HA et al. Effects of quadruple therapy: Zinc, Quercetin, Bromelain and Vitamin C on clinical outcomes of patients infected with COVID-19. Rea Int Jou of End and Dia 2020; 1:1005.
Colunga Biancatelli RM, Berrill M, Mohammed YH et al. Melatonin for the treatment of sepsis: the scientific rationale. J Thorac Dis 2020; 12 (Suppl 1):S54-S65.
 Reiter RJ, Abreu-Gonzalez P, Marik PE et al. Therapeutic algorithm for use of melatonin in patients with COVID-19. Front Med 2020; 7:226.
Reiter RJ, Sharma R, Ma Q et al. Melatonin inhibits COVID-19-induced cytokine storm by reversing aerobic glycolysis in immune cells: A mechanistic analysis. Medicine in Drug Discovery 2020; 6:100044.
Zhang R, Wang X, Ni L et al. COVID-19: Melatonin as a potential adjuvant treatment. Life Sci 2020; 250:117583.
Kleszczynski K, Slominski AT, Steinbrink K et al. Clinical trials for use of melatonin to fight COVID-19 are urgently needed. Nutrients 2020; 12.
Coto-Montes A, Boga JA. ER stress and autophagy induced by SARS-CoV-2: The targer for melatonin treatment. Melatonin Res 2020; 3:346-61.
Gandolfi JV, Di Bernardo AP, Chanes DA et al. The effects of melatonin supplementation on sleep quality and assessment of the serum melatonin in ICU patients: A randomized controlled trial. Crit Care Med 2020.
Castillo RR, Quizon GR, Juco MJ et al. Melatonin as adjuvant treatment for coronavirus disease 2019 pneumonia patients requiring hospitalization (MAC-19 PRO): a case series. Melatonin Res 2021; 3:297-310.
Ramiall V, Zucker J, Tatonetti N. Melatonin is significantly associated with survival of intubated COVID-19 patients. medRxiv 2021.
Farnoosh G, Akbaariqomi M, Badri T et al. Efficacy of a low dose of melatonin as an adjunctive therapy in hospitalized patients with COVID-19: A randomized, double-blind clinical trial. medRxiv 2021. 

Shneider A, Kudriavtsev A, Vakhusheva A. Can melatonin reduce the severity of COVID-19 pandemic. medRxiv 2020.
Rattis BA, Ramos SG, Celes MR. Curcumin as a potential treatment for COVID-19. Fronteirs in Pharmacology 2021; 21:675287.
Chai YS, Chen YQ, Lin SH et al. Curcumin regulates the differentiation of naive CD4+ T cells and activates IL-10 immune modulation against acute lung injury in mice. Biomedicine and Pharmacotherapy 2020; 125:109946.
Thimmulappa RK, Mudnakudu-Nagaraju KK, Shivamallu C et al. Antiviral and immunomodulatory activity of curcumin: A case for prophylactic therapy for COVID-19. Heliyon 2021; 7:e06350.
Jena AB, Kanungo N, Nayak V et al. Catechin and curcumin interact with S protein of SARS-CoV2 and ACE2 of human cell membrane: insights from computational studies. Scientific Reports 2021; 11:2043.
Somi VK, Mehta A, Ratre YK et al. Curcumin, a traditional spice component, can hold promise against COVID-10? Eur J Pharmacol 2020; 886:173551.
Tahmasebi S, El-Esawi MA, Mahmoud ZH et al. Immunomodulatory effects of nanocurcumin on the Th17 cell responses in mild and severe COVID-19 patients. J Cell Physiol 2021; 236:5325-38.
Valizadeh H, Danshina S, Gencer MZ et al. Nano-curcumin therapy, a promising method in modulating inflammatory cytokines in COVID-19 patients. International Immunopharmacology 2020; 89:107088.
Al-Hatamleh MA, Hatmal MM, Sattat K et al. Antiviral and immnomodulatory effects of phytochemicals from honey against COVID-19: Potential mechanisms of action and future directions. Molecules 2020; 25:5017.
Hashem HE. In Silico approach of some selected honey constituents as SARS-CoV-2 main protease (COVID-19) inhibitors. medRxiv 2021.
Ashraf S, Ashraf S, Ashraf M et al. Honey and Nigella sativa against COVID-19 in Pakistan (HNS-COVID-PK): A multi-center placebo-controlled randomized clinical trial. medRxiv 2021.
Salim B, Noureddine M. Identification of compounds from Nigella Sativa as new potential inhibitors of 2019 Novel Coronavirus (COVID-10): Molecular docking study. ChemRxiv 2021.
Fakhar-e-Alam Kulyar M, Li R, Mehmood K et al. Potential influence of Nagella sativa (Black cumin) in reinforcing immune system: A hope to decelerate the COVID-19 pandemic. Phytomedicine 2021; 85:153277.
Khazdair MR, Ghafari S, Sadeghi M. Possible therapeutic effects of Nigella sativa and its thymoquinone on COVID-19. Pharmaceutical Biology 2021; 59:696-703.
Islam MN, Hossain KS, Sarker PP et al. Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID-19 prevention and cure. Phytotherapy Research 2021; 35:1329-44.
Rahman MT. Potential benefits of combination of Nigella sativa and Zn supplements to treat COVID-19. J Herbal Med 2020; 23:100382.
Hannan MA. Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety. Nutrients 2021; 13.
Maghbooli Z, Sahraian MA, Ebrahimi M et al. Vitamin D sufficiency, a serum 25-hydroxyvitamin D at least 30 ng/ml reduced risk for adverse clinical outcomes in patients with COVID-19 infection. PloS ONE 2020; 15:e0239799.
Grant WB, Lahore H, McDonnell SL et al. Evidence that Vitamin D supplementation could reduce risk of influenza and COVID-19 infections and deaths. Nutrients 2020; 12:988.
Kaufman HW, Niles JK, Kroll MH et al. SARS-CoV-2 positivity rates associated with circulating 25-hydroxyvitamin D level. PloS ONE 2020; 15:e0239252.
Lau FH, Majumder R, Torabi R et al. Vitamin D insufficiency is prevalent in severe COVID-19. medRxiv 2020.
Marik PE, Kory P, Varon J. Does vitamin D status impact mortlality from SARS-CoV-2 infection? Medicine in Drug Discovery 2020.
Rhodes JM, Subramanian S, Laird E et al. Editorial: Low population mortality from COVID-19 in countries south of 35 degrees North - supports vitamin D as a factor determining severity. Alimentary Pharmacology & Therapeutics 2020; (in press).
Dancer RC, Parekh D, Lax S et al. Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax 2015; 70:617-24.
LLie PC, Stefanescu S, Smith L. The role of vitamin D in the prevention of coronavirus disease 2019 infection and mortality. Aging Clin Exp Res 2020.
Daneshkhah A, Eshein A, Subramanian H. The role of vitamin D in suppressing cytokine storm of COVID-19 patients and associated mortality. medRxiv 2020.
Bergman P, Lindh AU, Bjorkhem-Bergman L et al. Vitamin D and respiartory tract infections: A systematic review and meta-analysis of randomized controlled trials. PloS ONE 2013; 8:e65835.
Carpagnano GE, Lecce V, Quaranta VN et al. Vitamin D deficiency as a predictor of poor prognosis in patients with acute respiratory fialure due to COVID-19. J Endocrinol Invest 2020.
Israel A, Cicurel A, Feldhamer I et al. The link between vitamin D deficiency and Covid-19 in a large population. medRxiv 2020.
Radujkovic A, Hippchen T, Tiwari-Heckler S et al. Vitamin D deficiency and outcome of COVID-19 patients. Nutrients 2020; 12:2757.
Rizzoli R. Vitamin D supplementation: upper limit for safety revisited. Aging Clin Exp Res 2020.
Annweiler C, Hanotte B, de L'Eprevier CG et al. Vitamin D and survival in COVID-19 patients: A quasi-experimental study. Journal of Steroid Biochemistry & Molecular Biology 2020.
Moozhipurath RK, Kraft L, Skiera B. Evidence of protective role of Ultraviolet-B (UVB) radiation in reducing COVID-19 deaths. Nature Research 2020; 10:17705.
Cangiano B, Fatti LM, Danesi L et al. Mortality in an Italian nursing home during COVID-19 pandemic: correlation with gender, age, ADL, vitamin D supplementaion, and limitations of the diagnostic tests. Aging 2020; 12.
De Smet D, De Smet K, Herroelen P et al. Serum 25(OH)D level on hospital admission assocaited with COVID-19 stage and mortality. Am J Clin Pathol 2020.
Cozier YC, Castro-Webb N, Hochberg NS et al. Lower serum 25(OH) D levles associated with higher risk of COVID-19 infection in U.S. black women. PloS ONE 2021; 16:e0255132.
Murai IH, Fernandes AL, Sales LP et al. Effect of vitamin D3 supplementaion vs placebo on hospital length of stay in patients with severe COVID-19: A multicenter, double-blind, randomized controlled trial. JAMA 2020.
Wu Y, Cheng X, Jiang G et al. Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization. npj Biofilms and Microbiomes 2021; 7:61.
Hazan S, Stollman N, Bozkurt H et al. The missing microbes: Bifidobacterium and Faecalibacterium depletion and loss of microbiome diversity as potential susceptibility markers for SARS-CoV-2 infection and severity. Clinical Gastroenterology & Hepatology 2021.
Din AU, Mazhar M, Waseem M et al. SARS-CoV-2 microbiome dysbiosis linked disorders and possible probiotic role. Biomedicine & Pharmacotherapy 2021; 133:110947.
Yeoh YK, Zuo T, Lui GC et al. Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Gut 2021; 70:698-706.
Rosa DD, Dias MM, Grzeskowiak LM et al. Milk kefir: nutritional, micobiological and health benefits. Nutrition Research Reviews 2017; 30:82-96.
Kim DH, Jeong D, Kim H et al. Modern perspectives on the health benefits of kefir in next generation sequencing era: Improvement of the host gut microbiota. Critical Reviews in Food Science and Nutrition 2019; 59:1782-93.
Maggini S, Beveridge S, suter M. A combination of high-dose vitamin C plus zinc for the common cold. Journal of International Medical Research 2012; 40:28-42.
Colunga Biancatelli RM, Berrill M, Catravas JD et al. Quercetin and Vitamin C: experimental therapy for the prevention and treatment of SARS-CoV-2 via synergistic action. Front Immunol 2020.
Kyung Kim T, Lim HR, Byun JS. Vitamin C supplementaion reduces the odds of developing a common cold in Republic of Korea Army recruits: a randomised controlled trial. BMJ Mil Health 2020.
Colunga Biancatelli RM, Berrill M, Marik PE. The antiviral properties of vitamin C. Expert Rev Anti Infect Ther 2020; 18:99-101.
Hiedra R, Lo KB, Elbashabsheh M et al. The use of IV vitamin C for patients with COVID-19: a case series. Exp Rev Anti Infect Ther 2020.
Chen L, Li J, Luo C et al. Binding interaction of quercetin-3-B-galactoside and its synthetic derivatives with SARS-CoV 3CL: structure-activity relationship reveal salient pharmacophore features. Bioorganic & Medicinal Chemistry Letters 2006; 14:8295-306.
Nain Z, Rana HK, Lio P et al. Pathogenic profiling of COVID-19 and SARS-like viruses. Briefings in Bioinformatics 2020.
Yi L, Li Z, Yuan K et al. Small molecules blocking the entry of severe respiratory syndrome coronavirus into host cells. J Virol 2020; 78:11334-39.
Shakoor H, Feehan J, Dhaheri AS et al. Immune-boosting role of vitamins D,C,E, zinc, selenium and omega-3 fatty acids: could they help against COVID-19. Maturitas 2020.
Abian O, Ortega-Alarcon D, Jimenez-Alesanco A et al. Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening. International Journal of Biological Macromolecules 2020; 164:1693-703.
Hemila H, Carr A, Chalker E. Vitamin C may increase the recovery rate of outpatient cases of SARS-CoV-2 infection by 70%: reanalysis of the COVID A to Z randomized clinical trial. Research Square 2021.
Marik PE. Hydrocortisone, Ascorbic Acid and Thiamine (HAT therapy) for the treatment of sepsis. Focus on ascorbic acid. Nutrients 2018; 10:1762.
Marik PE. Vitamin C for the treatment of sepsis: The scientific rationale. Pharmacol Therapeut 2018; 189:63-70.
Chen L, Li J, Luo C et al. Binding interaction of quercetin-3-B-galactoside and its synthetic derivatives with SARS-CoV 3CLpro: Structure-activity relationship studies revela salient pharmacophore features. Bioorganic & Medicinal Chemistry 2020; 14:8295-306.
Ono K, Nakane H. Mechanisms of inhibition of various cellular DNA and RNA polymerases by several flavonoids. J Biochem 1990; 108:609-13.
Nair MP, Kandaswami C, Mahajan S et al. The flavonoid, quercetin, differentially regulates Th-1 (INF) and Th-2 (IL4) cytokine gene expression by normal peripheral blood mononuclear cells. Biochimica et Biophysica Acta 2020; 1593:29-36.
Saeedi-Boroujeni A, Mahmoudian-Sani MR. Anti-inflammatory potential of Quercetin in COVID-19 treatment. J Inflamm 2021; 18:3.
Dabbagh-Bazarbachi H, Clergeaud G, Quesada IM et al. Zinc ionophore activity of Quercetin and Epigallocatechin-gallate:From Hepa 1-6 cells to a liposome model. J Agric Food Chem 2014; 62:8085-93.
Nieman DC, Simonson A, Sakaguchi CA et al. Acute Ingestion of a Mixed Flavonoid and Caffeine Supplement Increases Energy Expenditure and Fat Oxidation in Adult Women: A Randomized, Crossover Clinical Trial. Nutrients 2019; 11.
Giuliani C, Bucci I, Di Santo S et al. The flavonoid quercetin in hibits thyroid-restricted genes expression and thyroid function. Food and Chemical Toxicology 2014; 66:23-29.
de Souza dos Santos MC, Goncalves CF, Vaisman M et al. Impact of flavonoids on thyroid function. Food and Chemical Toxicology 2011; 49:2495-502.
Chandra AK, De N. Catechin induced modulation in the activities of thyroid hormone synthesizing enzymes leading to hypothyroidism. Mol Cell Biochem 2013; 374:37-48.
Pistollato F, Masias M, Agudo P et al. Effects of phytochemicals on thyroid function and their possible role in thyroid disease. Ann N Y Acad Sci 2019; 1433:3-9.
Sathyapalan T, Manuchehri AM, Thatcher NJ et al. The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: A randomized, double-blind, crossover study. J Clin Endocrinol Metab 2020; 96:1422-49.
Tonstad S, Jaceldo-Siegl K, Messina M et al. The association between soya consumption and serum thyroid-stimulating hormone in the Adventist Health Study-2. Public Health Nutr 2016; 19:1464-70.
Colombo D, Lunardon L, Bellia G. Cyclosporine and herbal supplement interactions. Journal of Toxicology 2014; 2014:145325.

Vogel-Gonzalez M, Tallo-Parra M, Herrera-Fernandez V et al. Low zinc levels at admission associates with poor clinical outcomes in SARS-CoV-2 infection. Nutrients 2021; 13:562.
te Velthuis AJ, van den Worm SH, Sims AC et al. Zn2+ inhibits Coronavirus and Arterivirus RNA polymerase activity In Vitro and Zinc ionophores block the replication of these viruses in cell culture. PLos Pathog 2010; 6:e1001176.
Shakoor H, Freehan J, Mikkelsen K et al. Be well: A potential role for vitamin B in COVID-19. Maturitas 2020.
dos Santos LM. Can vitamin B12 be an adjuvant to COVID-19 treatment? GSC Biological and Pharmaceutical Sciences 2020; 11.
Tan CW, Ho LP, Kalimuddin S et al. Cohort study to evaluate effect of vitamin D, magnesium, and vitamin b12 in combination on severe outcome progression in older patients with coronavirus (COVID-19). Nutrition 2020; 80:111017.

Zhang P, Tsuchiya K, Kinoshita T et al. Vitamin B6 prevents IL-1B  protein production by inhibiting NLRP3 inflammasome activation. J Biol Chem 2020; 291:24517-27.
Bianconi V, Violi F, Fallarino F et al. Is acetylsalicylic acid a safe and potentially useful choice for adult patients with COVID-19? Drugs 2020.
Muller C, Karl N, Ziebuhr J et al. D,L-lysine acetylsalicylate + glycine impairs coronavirus replication. J Antivir Antiretovir 2020.
Cakman I, Kirchner H, Rink L. Zinc supplementation reconstitutes the production of interferon-alpha by leukocytes from elderly persons. J Interferon Cytokine Res 1997; 17:469-72.
Cheng RZ. Can early and high-dose vitamin C prevent and treat coronavirus disease 2019 (COVID-19). Medicine in Drug Discovery 2020.
Wang Y, Lin H, Lin BW et al. Effects of different ascorbic acid doses on the mortality of critically ill patients: a meta-analysis. Ann Intensive Care 2019; 9:58.
Boretti A, Banik BK. Intravenous vitamin C for reduction of cytokines storm in acute respiratory distress syndrome. PharmaNutrition 2020; 12:100190.
Iglesias J, Vassallo AV, Patel V et al. Outcomes of metabolic resuscitation using ascorbic acid, thiamine, and glucocorticoids in the early treatment of sepsis. Chest 2020; 158:164-73.
de Melo AF, Homem-de-Mello M. High-dose intravenous vitamin C may help in cytokine storm in severe SARS-CoV-2 infection. Crit Care 2020; 24:500.
Zhang J, Rao X, Li Y et al. High-dose vitamin C infusion for the treatment of critically ill COVID-19. Research Square 2020.
Kumari P, Dembra S, Dembra P et al. The role of vitamin C as adjuvant therapy in COVID-19. Cureus 2020; 12:e11779.
Al Sulaiman K, Al Juhani O, Badreldin HA et al. Adjunctive therapy with ascorbic in critically ill patients with COVID-19: A multicenter propensity score matched study. Crit Care 2021.
Lankadeva YR, Peiris RM, Okazaki N et al. Reversal of the pathophysiological responses to Gram-negative sepsis by megadose Vitamin C. Crit Care Med 2020.
Zhang J, Rao X, Li Y et al. Pilot trial of high-dose vitamin C in critically ill COVID-19 patients. Ann Intenisve Care 2020.
Patterson G, Isales CM, Fulzele S. Low level of vitamin C and dysregulation of vitamin C transporter might be involved in the severity of COVID-19 infection. Aging and Disease 2020; 12.
Tomassa-Irriguible TM, Lielsa-Berrocal L. COVID-19: Up to 87% critically ill patients had low vitamin C values. Research Square 2020.
Arvinte C, Singh M, Marik PE. Serum levels of vitamin C and vitamin D in a cohort of critically ill COVID-19 patients of a North American Community Hospital Intensive Care Unit in May 2020. A pilot study. Medicine in Drug Discovery 2020; 8:100064.
Menezes RR, Godin AM, Rodrigues FF et al. Thiamine and riboflavin inhibit production of cytokines and increase the anti-inflammatory activity of a corticosteroid in a chronic model of inflammation induced by complete Freund's adjuvant. Pharmacological Reports 2020; 69:1036-43.
Vatsalya V, Li F, Frimodig J et al. Therapeutic prospects for Th-17 cell immune storm syndrome and neurological symptoms in COVID-19: Thiamine efficacy and safety, In-vitro evidence and pharmacokinetic profile. medRxiv 2020.
Mallat J, Lemyze M, Thevenin D. Do not forget to give thiamine to your septic shock patient! J Thorac Dis 2016; 8:1062-66.
Moskowitz A, Donnino MW. Thiamine (vitamin B1) in septic shock: a targeted therapy. J Thorac Dis 2020; 12 (suppl 1):S78-S83.
Woolum JA, Abner EL, Kelly A et al. Effect of thiamine administration on lactate clearance and mortality in patients with septic shock. Crit Care Med 2018; 46:1747-52.
Marik PE. Thiamine: An essential component of the metabolic resuscitation protocol. Crit Care Med 2018; 46:1869-70.
Al Sulaiman K, Aljuhani O, Al Dossari M et al. Evaluation of thiamine as adjunctive therapy in COVID-19 critically ill patients: A multicenter propensity score matched study. Research Square 2021.

 


©Stowarzyszenie Farmaceutów Katolickich Polski 2022 O nas Diecezje Kontakt
Ta strona wykorzystuje pliki cookies w celu zapewnienia pełnej funkcjonalności serwisu